Yes, please. Is the standard to be screening with qualitative RNA for all PreP and PEP or only during therapy? As I understand the "science" behind the recommendation, ARV's delay the development of Antibodies thus Ab-based testing loses sensitivity. But with the current 4th generation test, and initial screening for P24 antigen, do ARV delay the emergence of P24?
I currently am using a mail-order lab system for PreP and it is working great for muy very rural patients or those that can not get to a lab between 7 and 4 M-F. I can check if they can do HIV RNA Qualitative via the blood drop on filter paper.
I wish there was more emphasis placed on extragenital screening
Obviously, I, al teast some training
------------------------------
Christine Brennan
LSU Health Sciences Center
New Orleans LA
------------------------------
Original Message:
Sent: 02-07-2022 12:31
From: Brian McMurray
Subject: New CDC PrEP Guidelines that include suggested new HIV Testing Algorithm
I would ask that someone address in detail the recently released new CDC Guidelines for PrEP in the next issue, if not already doing such, in the next edition of HIV Specialist and in an upcoming Academy Voice email
Good thing that the HIV RNA qualitative does not require refrigerated or frozen blood, unlike the HIV RNA quantitative (Viral Load).
With the new suggested guidelines of always having a negative HIV RNA qualitative confirmatory test….it seems to me that we might also alter the PEP Guidelines and protocol. Specifically, if a 6 week post PEP initiation lab shows a negative HIV RNA, after taking PEP meds for 28 days, would that not be enough to "close the case", instead of doing a 3 month follow up?
LBrian R. McMurray, MD, FACP, AAHIVS
Music City PrEP, Medical Director
615 Main St.
Nashville, TN 37206
cell 615-419-0428
------------------------------
Brian R. McMurray, MD, FACP, AAHIVS
Brentwood TN
------------------------------