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NRTI
Abacavir Ziagen Sensitive
RAMs*: M184M/V
Didanosine Videx Resistance Possible
RAMs*: M184M/V
Emtricitabine Emtriva Resistant
RAMs*: M184M/V
Lamivudine Epivir Resistant
RAMs*: M184M/V
Stavudine Zerit Sensitive 1
RAMs*: None
Tenofovir Viread Sensitive 2
RAMs*: None
Zidovudine Retrovir Sensitive 2
RAMs*: None
NNRTI
Doravirine Pifeltro Resistance Possible
RAMs*: K103K/N, D177D/N, Y181Y/C, G190G/A, H221Y,
V245V/E
Efavirenz Sustiva Resistant
RAMs*: K103K/N, Y181Y/C, G190G/A
Etravirine Intelence Resistance Possible
RAMs*: Y181Y/C, H221Y
Nevirapine Viramune Resistant
RAMs*: K103K/N, Y181Y/C, G190G/A
Rilpivirine Edurant Resistant
RAMs*: K103K/N, Y181Y/C, H221Y
INI
Bictegravir Bictegravir Sensitive
RAMs*: None
Dolutegravir Tivicay Sensitive
RAMs*: None
Elvitegravir Vitekta Sensitive
RAMs*: None
Raltegravir Isentress Sensitive
RAMs*: None
PI
Atazanavir/r Reyataz / r Resistant
RAMs*: K20K/V, M36I, K43K/T, M46M/I, I54I/V, D60E,
I62I/V, A71A/V, G73G/S, V82V/A, L90L/M
Darunavir/r Prezista / r Sensitive
RAMs*: E35E/N, K43K/T, M46M/I, G73G/S, L90L/M
Fosamprenavir/r Lexiva / r Resistant
RAMs*: E35E/N, K43K/T, M46M/I, I54I/V, G73G/S, V82V/A,
L90L/M
Indinavir/r Crixivan / r Resistant
RAMs*: E35E/N, M36I, M46M/I, I54I/V, A71A/V, G73G/S,
V82V/A, L90L/M
Lopinavir Kaletra Resistant
RAMs*: E35E/N, K43K/T, M46M/I, I54I/V, A71A/V, G73G/S,
V82V/A, L90L/M
Nelfinavir Viracept Resistant
RAMs*: M36I, M46M/I, I54I/V, A71A/V, G73G/S, V82V/A,
L90L/M
Ritonavir Norvir Resistant
RAMs*: K20K/V, K43K/T, I54I/V, A71A/V, G73G/S, V82V/A,
L90L/M
Saquinavir/r Invirase / r Resistant
RAMs*: K20K/V, E35E/N, K43K/T, I54I/V, I62I/V, A71A/V,
G73G/S, L90L/M
Tipranavir/r Aptivus / r Resistance Possible
RAMs*: E35E/N, M36I, K43K/T, I54I/V, A71A/V, L90L/M
*RAMs = Resistance Associated Mutations observed
Summary of Mutations Observed:
RT: P9P/S, K20K/R, V35V/I, S48T, S68S/G, Q102K/R, K103K/N,
K122P, I142I/V, C162S, D177D/N, Y181Y/C, M184M/V,
G190G/A, Q197E, T200A, I202V, E204E/K, H221Y, E233E/D,
P243S, V245V/E, D250D/E/K/N, R277K, T286A, A288S,
V293I, E297E/G, V317V/A, Q334Q/H, M357T, K358R,
A360A/V, A376S, T386I, K390R, A400S
IN: K14K/R, R20K, K34R, V72I, L101I, V113I, S119S/P, K156N,
V201I, V234L, D256E
PR: K20K/V, E35E/N, M36I, K43K/T, M46M/I, I54I/V, R57K,
D60E, I62I/V, L63P/S, I64I/V, C67C/F, A71A/V, I72I/T,
G73G/S, V82V/A, L90L/M
Assessment of drug susceptibility is based upon detected
mutations and interpreted using an advanced proprietary
algorithm (version 18).
Comments:
1 - Assessment for this drug was derived considering the
sensitizing effect of mutation M184V.
2 - Assessment for this drug was derived considering the
sensitizing effect of mutations Y181C and M184V.
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