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  • 1.  Crushing Meds for G-Tube

    Posted 08-06-2024 18:09

    Hi Everyone,

    I have a patient with perinatally acquired HIV and intellectual delays who can't swallow medication. Therefore, she gets everything via a G-tube. She is currently on liquid Abacavir, Zidovudine and Tivicay-PD all via the G-tube. She has now outgrown the Tivicay-PD dose. Has anyone ever had a patient crush and dissolve adult Tivicay 50mg in water and administer it in a G-tube? Did you do once daily or twice daily dosing?

    Thanks 



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    Lorato Anderson
    Trenton NJ
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  • 2.  RE: Crushing Meds for G-Tube

    Posted 08-09-2024 11:17
      |   view attached

    Hi Lorato,

    Unfortunately, there is not PK data supporting crushing film coated dolutegravir and placing in g-tube for administration per ViiV (please see attachment). We have a few patients that have crushed dolutegravir and placed in semi-solid food and drink and taken orally with success, but I see your patient has all medications administered via g-tube. If you have a genotype available, I could offer other recommendations that could be crushed and would be viable via g-tube. 



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    Susan Carr, AAHIVP, PharmD
    St. Jude Children's Research Hospital
    Memphis, Tennessee
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    Attachment(s)

    pdf
    Dolutegravir and NG tube.pdf   145 KB 1 version
    Original Message


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