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  • 1.  PEP "++" vs. PEP - MPX vaccine

    Posted 08-17-2022 13:04
    Can someone explain the difference? My understanding is that certain folks can get PEP (depending on their risk factors) even in the absence of a known exposure and this is known as PEP++. Is this correct? So it doesn't have anything to do with the actual dosing / type of vaccine right? Is only for certain states or is this nationwide? 

    Thanks all :)

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    Gina Tomkus
    San Diego CA
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  • 2.  RE: PEP "++" vs. PEP - MPX vaccine

    Posted 08-17-2022 16:45
    That is correct.  Dosing is the same.  States have reigns on stockpile allocation, so eligibility should fall to them.  Most are sticking to CDC guidance of PEP and PEP++, which basically boils down to asymptomatic recent known exposure, and asymptomatic recent highly likely exposure.

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    Dan Scales PharmD, AAHIVP
    Director of Pharmacy Collaborative Care
    Vivent Health
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    Original Message


  • 3.  RE: PEP "++" vs. PEP - MPX vaccine

    Posted 08-17-2022 18:38
    I agree with what Daniel said, just wanted to add this link to the CDC website that includes the definitions of both: https://www.cdc.gov/poxvirus/monkeypox/interim-considerations/overview.html#anchor_1660077319531

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    Caitlin Prather, PharmD, BCACP, AAHIVP, TTS
    Clinical Pharmacist in Fairfax, VA
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    Original Message


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