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  • 1.  Thrombocytopenia

    Posted 20 days ago

    Hello everyone,

    I hope you all are doing well. I would like to hear about clinical experiences and management of persistent thrombocytopenia in virally suppressed patients with a good immune response. I understand the incidence of thrombocytopenia is about 30-40% in patients with advanced HIV. But it is really appreciated it If I can hear of any successful treatment. 

    Thank you 



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    Randy Aguiar Ramos
    Miami FL
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  • 2.  RE: Thrombocytopenia

    Posted 19 days ago

    It would be good to know the platelet count. In most cases there's nothing required beyond effective ART, but that would be different for very low counts or evidence of bleeding.



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    Joel Gallant, MD, MPH
    Santa Fe, NM
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  • 3.  RE: Thrombocytopenia

    Posted 17 days ago

    Thank you very much Dr. Gallant. Patients in reference who are experiencing low platelets remain asymptomatic with no signs of bleeding. I really appreciate your comment. Thank you 



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    Randy Aguiar Ramos
    Miami FL
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  • 4.  RE: Thrombocytopenia

    Posted 19 days ago

    The thrombocytopenia is usually linked to the viral load and should improve with control of the viral load.

    This is kind of my thought process of common things to rule-out before I start a deeper dive:

    1. Concomittant other viral infections (Hep B and H. pylori)
    2. Nutritional deficiencies (B12, folate, copper) 
    3. Liver dysfunction
    4. Splenomegaly
    5. Medications (esp. TMP-SMX)


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    Francis Matuszak
    Miami Lakes FL
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  • 5.  RE: Thrombocytopenia

    Posted 17 days ago

    Thank you very much Francis for sharing your through process. Patients in reference are virologically suppressed. Thank you! 



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    Randy Aguiar Ramos
    Miami FL
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