Academy Exchange

Hello everyone,

I hope you all are doing well. I would like to hear about clinical experiences and management of persistent thrombocytopenia in virally suppressed patients with a good immune response. I understand the incidence of thrombocytopenia is about 30-40% in patients with advanced HIV. But it is really appreciated it If I can hear of any successful treatment. 

Thank you 

It would be good to know the platelet count. In most cases there's nothing required beyond effective ART, but that would be different for very low counts or evidence of bleeding.

Hello everyone,

I hope you all are doing well. I would like to hear about clinical experiences and management of persistent thrombocytopenia in virally suppressed patients with a good immune response. I understand the incidence of thrombocytopenia is about 30-40% in patients with advanced HIV. But it is really appreciated it If I can hear of any successful treatment. 

Thank you 

Hello everyone,

I hope you all are doing well. I would like to hear about clinical experiences and management of persistent thrombocytopenia in virally suppressed patients with a good immune response. I understand the incidence of thrombocytopenia is about 30-40% in patients with advanced HIV. But it is really appreciated it If I can hear of any successful treatment. 

Thank you 

The thrombocytopenia is usually linked to the viral load and should improve with control of the viral load.

This is kind of my thought process of common things to rule-out before I start a deeper dive:

1. Concomittant other viral infections (Hep B and H. pylori)
2. Nutritional deficiencies (B12, folate, copper) 
3. Liver dysfunction
4. Splenomegaly
5. Medications (esp. TMP-SMX)

Hello everyone,

I hope you all are doing well. I would like to hear about clinical experiences and management of persistent thrombocytopenia in virally suppressed patients with a good immune response. I understand the incidence of thrombocytopenia is about 30-40% in patients with advanced HIV. But it is really appreciated it If I can hear of any successful treatment. 

Thank you