I am Dr Alok Vashishtha from Haridwar, India.
A 24 year old boy case history was received by us for opinion on 10th April 2022. This boy is on ART from 04th January, 2006. The treatment history is provided in table below. As his HIV-1 Drug Resistance Testing was never done before, so we got it done and it showed resistance to no drugs. Genotype Resistance Test report attached in two parts for reference. We thought it as the case of non-adherence and with detailed enquiry patient told us that he was taking Darunavir 600 mg + Ritonavir 100 mg only once daily. So we made it now to twice daily and will repeat HIV RNA Quantitative RT-PCR after 6 weeks. My concern is why Genotype resistance testing is showing all drugs susceptible. Just to add that we got Genotype resistance testing repeated at another lab and it showed same pattern.
Looking forward your valuable opinion for our patient.
HIV RNA QUANTITATIVE RT-PCR (Copies/ml)
D4T, 3TC, NVP
AZT, 3TC, NVP
AZT, 3TC. NVP
ATV/r, TDF, STC
ATV/r, TDF, 3TC
DRV/r, DTG (12 hourly)
With best regards
Dr Alok Vashishtha
MBBS, MDHM, FIHM, AAHIVS
Centre for Infectious Diseases,