Currently in South Africa, the following ART are available in both public and private sectors:
TLD (TDF/3TC/DTG 300/300/50 mg) STR
ALD (ABC/3TC/DTG 600/300/50 mg) STR
TEE (TDF/FTC/EFV 300/200/600 mg) STR
TDF/FTC 300/200 mg
ABC/3TC 600/300 mg
AZT/3TC 300/150 mg
LPV/r (200/50 mg)
ATV/r (300/100 mg)
Patients in the private sector can access Rilpivirine and TAF but unfortunately not STR.
I did not list the current third-line regimens (guided by the genotype/resistance that might include DRV/r, ETV and DTG) following PI/r failure mainly acquired through the Department of Health and did not mention pediatric ones.
Considering that he is travelling that easily, he should if under a good clinician and insurance be able to access TAF if needed
Regards
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Dominique Kabengele-Kayembe
Heidelberg, South Africa
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Original Message:
Sent: 03-15-2024 12:34
From: Paul Sacamano
Subject: ART regimens available in South Africa
Hi colleagues! I have a patient new to me originally from South Africa. He's been taking EFV and 3TC/AZT for years with a history of depression and anemia--need to switch his regimen and ideally avoid TDF.
The challenge is that he'll be traveling back and forth between the US and South Africa for months at a time and we need to find a regimen that is available in both countries.
From my research into the Southern African HIV Clinicians Society, the recommended regimen is TDF/3TC and DTG, but we need to avoid TDF given history of renal disease.
Does anyone know of other ART regimens available in South Africa or can point me to a resource where I can find the answer?
Thanks!
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Paul Sacamano, PhD, MPH, NP-C
El Rio Health
Tucson AZ
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