Academy Exchange

 View Only
  • 1.  HCV- Epclusa failure

    Posted 12-06-2023 07:18

    We have a Hep C  patient who completed his 12 week regimen of Epclusa with a viral load dropping from 561,000 to 464 during treatment, and at 3 months post his VL is now 4,666,000. Genotype 3. He is compliant, has no risk of re-exposure. Non-cirrhotic, no jaundice, no ascites- overall healthy. No co-infections. Abd US- mild hepatomegaly, no focal discrete mass. 

    Ns5a testing recently completed with PROBABLE aclatasvir and velpatasvir drug resistance. His insurance is requiring Vosevi for re-treatment.  We are recommending Mavyret, especially due to probable resistance.  Is Vosevi a truly viable option/ recommended? Any guidance appreciated. 

    Janis Oenbrink, FNP-C, AAHIVS

  • 2.  RE: HCV- Epclusa failure

    Posted 12-06-2023 21:54

    What was his previous genotype?

    Michael Potnek
    Outreach Community Health Centers
    Menomonee Falls WI

  • 3.  RE: HCV- Epclusa failure

    Posted 12-07-2023 06:34

    Same, 3 (Not a re-infection) 

    Janis Oenbrink
    Titusville FL